Research and review papers in peer review journals
Salehi B, Mishra AP, Nigam M, Karazhan N, Shukla I, Kiełtyka-Dadasiewicz A, Sawicka B, Głowacka A, Abu-Darwish MS, Tarawneh AH, Gadetskaya AV, Cabral C, Salgueiro L, Victoriano M, Martorell M, Docea AO, Abdolshahi A, Calina D, Sharifi-Rad J. 2021. Ficus plants: state of the art from a phytochemical, pharmacological, and toxicological perspective. Phytotherapy Research 35(3): 1187-1217. DOI: 10.1002/ptr.6884. LINK
Beeby E, Magalhães M, Lemos MFL, Pires IM, Cabral C. 2021. Cytotoxic effects of Ridolfia segetum (L.) Moris phytoproducts in cancer cells. Journal of Ethnopharmacology 267(1): Article ID 113515. DOI: 10.1016/j.jep.2020.113515. LINK
Moukette BM, Castelão-Baptista JP, Ferreira L, Silva AM, Simões RF, Cabral C, Pieme CA, Ngogang JY, Sardão VA, Oliveira PJ. 2021. Afrostyrax lepidophyllus Mildbr. and Monodora myristica (Gaertn.) Dunal extracts decrease doxorubicin cytotoxicity on H9c2 cardiomyoblasts. Evidence-Based Complementary and Alternative Medicine 2021: Article ID 8858165, 12 pages. DOI: 10.1155/2021/8858165. LINK
Magalhães M, Manadas B, Efferth T, Cabral C. 2021. Chemoprevention and therapeutic role of essential oils and phenolic compounds: modeling tumor microenvironment in glioblastoma. Pharmacological Research 169: Article ID 105638. DOI: 10.1016/j.phrs.2021.105638. LINK
Paiva-Santos AC, Mascarenhas-Melo F, Coimbra SC, Pawar KD, Peixoto D, Chá-Chá R, Pereira AA, Cabral C, Pinto S, Veiga F. 2021. Nanotechnology-based formulations towards the improved topical delivery of anti-acne active ingredients. Expert Opinion on Drug Delivery 18(10): 1435-1454. DOI: 10.1080/17425247.2021.1951218. LINK
Melim C, Lauro MR, Pires IM, Oliveira PJ, Cabral C. 2022. The role of glucosinolates from cruciferous vegetables (Brassicaceae) in gastrointestinal cancers: from prevention to therapeutics. Pharmaceutics, Section: Biopharmaceutics, Special Issue: Herbal Extracts and Natural Compounds: Nutraceutical and Pharmaceutical Aspects Volume II 14(1): 190. DOI: 10.3390/pharmaceutics14010190. LINK
Melim C, Magalhães M, Paiva-Santos AC, Campos E, Cabral C. 2022. Nanoparticles as phytochemical carriers for cancer treatment: news of the last decade. Expert Opinion on Drug Delivery 19(2): 179-197. DOI: 10.1080/17425247.2022.2041599. LINK
Oliveira S, Monteiro-Alfredo T, Henriques R, Ribeiro CF, Seiça R, Cruz T, Cabral C, Fernandes R, Piedade F, Robalo MP, Paulo Matafome P, Silva S. 2022. Improvement of glycaemia and endothelial function by a new 2 low-dose curcuminoid in an animal model of type 2 diabetes. International Journal of Molecular Sciences. Special issue: Molecular Pharmacology in Diabetes 23(10): 5652. DOI: 10.3390/ijms23105652. LINK
Domínguez-Martín EM, Magalhães M, Díaz-Lanza AM, Marques MP, Princiotto S, Gomez AM, Efferth T, Cabral C, Patricia Rijo. 2022. Phytochemical study and anti-glioblastoma activity assessment of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger var. hadiensis stems. Molecules 27(12): 3813. Special issue: Drug Development Inspired by Natural Products. DOI: 10.3390/molecules27123813. LINK
Magalhães M, Domínguez-Martín EM, Jorge J, Gonçalves AC, Díaz-Lanza AM, Manadas B, Efferth T, Rijo P, Cabral C. 2022. Parvifloron D-based potential therapy for glioblastoma: inducing apoptosis via the mitochondria dependent pathway. Frontiers in Pharmacology, Section: Experimental Pharmacology and Drug Discovery, Special issue: Considering Plant Metabolites and Their Synthetic Derivatives as Candidates for the Development of Drugs Directed Against Multidrug Resistant (MDR) Tumors. DOI: 10.3389/fphar.2022.1006832. LINK
Varela C, Melim C, Guapo-Neves B, Sharifi-Rad J, Calina D, Mamurova A, Cabral C. 2022. Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms. Journal of Translational Medicine 20: 630. DOI: 10.1186/s12967-022-03828-3. LINK
Marques MP, Neves BG, Varela C, Zuzarte M, Gonçalves AC, Dias MI, Amaral JS, Barros L, Magalhães M, Cabral C. 2023. Essential oils from Côa Valley Lamiaceae species: cytotoxicity and antiproliferative effect on glioblastoma cells. Pharmaceutics, Section: Biologics and Biosimilars, Special issue: Advances in Natural Products and Their Derivatives for Metabolic and Chronic Inflammatory Disease Therapy 15 (2): 342. DOI: 10.3390/pharmaceutics15020341. LINK
Marques MP, Mendonça L, Neves BG, Varela C, Oliveira PJ, Cabral C. 2023. Exploring Iberian Peninsula Lamiaceae as potential therapeutic approaches in wound healing. Pharmaceuticals, Section: Natural Products 16 (3): 347. DOI: 10.3390/ph16030347. LINK
Ferreira BP, Costa G, Mascarenhas-Melo F, Pires PC, Heidarizadeh F, Giram PS, Mazzola PG, Cabral C, Veiga F, Paiva-Santos AC. 2023. Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety. Phytochemistry Reviews. DOI: 10.1007/s11101-023-09860-5. LINK
Marques MP, Varela C, Mendonça L, Cabral C. 2023. Nanotechnology-based topical delivery of natural products for the management of atopic dermatitis. Pharmaceutics, Section: Nanomedicine and Nanotechnology, Special issue: Nanotechnology and Natural Products: Plant Bioactive Compounds for Drug Delivery (Volume II) 15 (6): 1724. DOI: 10.3390/pharmaceutics15061724 LINK
Monteiro-Alfredo T, dos Santos JM, Antunes KÁ, Cunha J, da Silva Baldivia D, Pires AS, Marques I, Abrantes AM, Botelho MF, Monteiro L, Gonçalves AC, Botelho WH, Paula de Araújo Boleti A, Cabral C, Oliveira PJ, Lucas dos Santos E, Matafome P, de Picoli Souza K. 2023. Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer activity. Frontiers in Pharmacology 14, Section: Pharmacology of anti-cancer drugs. DOI: 10.3389/fphar.2023.1223933. LINK
Frija LMT, Guerreiro BEC, Costa ICC, Isca VMS, Saraiva L, Neves BG, Magalhães M, Cabral C, Cristiano MLS, Rijo P. 2023. Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents. Exploration of Drug Science 2023, 1: 420–434. DOI: 10.37349/eds.2023.00028. LINK
Pais ML, Teixeira M, Soares C, Lima G, Rijo P, Cabral C, Castelo-Branco M. 2024. Rapid effects of tryptamine psychedelics on perceptual distortions and early visual cortical population receptive fields. Neuroimage 297: 120718. DOI: 10.1016/j.neuroimage.2024.120718. LINK
Magalhães M, Domínguez-Martín Eva, Jorge J, Gonçalves AC, Massenzio F, Spigarelli R, Ribeiro-Rodrigues T, Catarino S, Girão H, Monti, B, Spisni E, Ferreira L, Oliveira PJ, Efferth T, Rijo P, Cabral C. 2024. Unveiling the antitumor mechanism of 7α-acetoxy-6β-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma. Journal of Ethnopharmacology 335: 118689. DOI: 10.1016/j.jep.2024.118689. LINK
Pires PC, Motallebi M, Marques MP, Correia M, Sharma A, Damiri F, Hameed H, Singh SK, Dua K, Jha NK, Cabral C, Veiga F, Paiva-Santos AC. 2024. Mentha aquatica (water mint) as a source of active pharmaceutical and cosmetic ingredients: a critical review. Phytotherapy Research 38(12): 5806-5839. DOI: 10.1002/ptr.8337. LINK
Gonçalves MBS, Marques MP, Correia F, Pires PC, Correia M, Makvandi P, Varela C, Cefali LC, Mazzola PG, Veiga F, Cabral C, Mascarenhas-Melo F, Paiva-Santos AC. 2024. Wine industry by-products as a source of active ingredients for topical applications. Phytochemistry Reviews. DOI: 10.1007/s11101-024-10030-4. LINK
Soares C, Lima G, Pais ML, Teixeira M, Cabral C, Castelo-Branco M. 2024. Increased functional connectivity between brain regions involved in social cognition, emotion and affective-value in psychedelic states induced by N,N-Dimethyltryptamine (DMT). Frontiers in Pharmacology 15, Section: Neuropharmacology. DOI: 10.3389/fphar.2024.1454628. LINK
Parente R, Paiva-Santos AC, Cabral C, Costa GF. 2025. Comprehensive review of Urtica dioica L. (Urticaceae) phytochemistry and anti-inflammatory properties. Phytochemistry Reviews 24: 1591-1628. DOI: 10.1007/s11101-024-09980-6. LINK
Spigarelli R, Spisni E, Magalhães M, Cabral C, Gonçalves AC, Saracino IM, Botti G, Dalpiaz A, Beggiato S, Valerii MC. 2025. Clove essential oil as a source of antitumoral compounds capable of crossing the blood brain barrier: a focus on the effects of β-Caryophyllene and Eugenol in a glioblastoma cell line. International Journal of Molecular Sciences, Section: Bioactives and Nutraceuticals, Special issue: Phytochemicals and Nutrients in Cancer Prevention and Treatment: Recent Trends and Advances, 2nd Edition 26 (1): 238. DOI: 10.3390/ijms26010238. LINK
Amorim R, Melim C, Marques MP, Varela C, Sardão VA, Teixeira J, Dias MI, Barros L, Oliveira PJ, Cabral C. 2025. Chemical characterization and differential lipid-modulating effects of selected plant extracts from Côa Valley (Portugal) in a cell model for Liver Steatosis. Pharmaceuticals 18(1): 39. DOI: 10.3390/ph18010039. LINK
Fernandes L, Paiva DS, Pereira E, Rufino AC, Landim E, Marques MP, Cabral C, Portugal A, Mesquita N. 2025. Evaluating the antifungal activity of volatilized essential oils on fungi contaminating artifacts from a Museum Collection. Applied Sciences 15: 2378. DOI: 10.3390/app15052378. LINK
Amorim R, Marques MP, Varela C, Dias MI, Barros L, Teixeira J, Oliveira PJ, Cabral C. 2025. Mechanistic Insights into Equisetum ramosissimum-Mediated Protection Against Palmitic Acid-Induced Mitochondrial Dysfunction and Oxidative Stress in a Cell Model for Liver Steatosis. Food Bioscience 72: 107483. DOI: 10.1016/j.fbio.2025.107483. LINK
Pires PC, Magalhães M, Cabral C, Veiga F, Mazzola PG, Paiva-Santos, AC. 2025. Development and characterization of novel intranasal in situ thermoreversible ketoprofen-loaded nanoemulgels for the treatment of glioblastoma. Journal of Drug Delivery Science and Technology 114, Part B: 107580. DOI: 10.1016/j.jddst.2025.107580. LINK
Lima G, Soares C, Teixeira M, Pais M, Rijo P, Cabral C, Castelo-Branco M. 2025. Inhaled N,N-Dimethyltryptamine Diminishes Connectivity between the Ventral Tegmental Area and the Nucleus Accumbens: relevance to pathologies of mesolimbic and mesocortical pathways. Scientific Reports. DOI: 10.1038/s41598-025-31431-1. LINK
Akegbe E, Mesquita N, Cabral C, Pereira E, Fernandes L, Carmo A, Tomé R, Pinheiro D, Pinheiro-Costa J, Rosa AM, Campos EJ. 2025. In Vitro Antifungal Effect of Selected Essential Oils Against Clinical Isolates Causing Fungal Keratitis: A Preliminary Pharmacological Evaluation. Future Pharmacology 5(4): 73. DOI: 10.3390/futurepharmacol5040073. LINK
Marques MP, Landim E, Varela C, Costa R, Marques J, Carvalho LAEB, Silva A, Cruz T, André R, Rijo P, Dias MI, Carvalho A, Oliveira PJ, Cabral C. 2025. A spectrochemical-driven study: depicting phenolic-rich extracts from Helichrysum stoechas, Lavandula pedunculata and Thymus mastichina to revert skin aging effects. Pharmaceuticals 18(12): 1889. DOI: 10.3390/ph18121889. LINK
Lima G, Soares C, Teixeira M, Pais M, Rijo P, Cabral C, Castelo-Branco M. 2026. Inhaled N,N-Dimethyltryptamine Diminishes Connectivity between the Ventral Tegmental Area and the Nucleus Accumbens: relevance to pathologies of mesolimbic and mesocortical pathways. Scientific Reports 16: 1744. DOI: 10.1038/s41598-025-31431-1. LINK
Marques MP, Landim E, Varela C, Costa R, Marques J, Carvalho LAEB, Silva A, Cruz T, André R, Rijo P, Dias MI, Carvalho A, Oliveira PJ, Cabral C. 2026. Targeting skin aging hallmarks in vitro: the antioxidant, anti-inflammatory and antisenescence effects by phenolics-rich extracts from Cistus L. species. Antioxidants, Section: Health Outcomes of Antioxidants and Oxidative Stress, Special issue: Natural Antioxidants for Cosmetic Applications 15(1): 149. DOI: 10.3390/antiox15010149. LINK
Magalhães M, Spigarelli R, Domínguez-Martín EM, Ferreira Lino, Efferth T, Rijo P, Spisni E, Cabral C. 2026. 7α-Acetoxy-6β-Hydroxyroyleanone (Roy) Mediates Neuroinflammatory Inhibition and Tumor Suppression in Glioblastoma. Frontiers in Pharmacology 14, Section: Ethnopharmacology, Research Topic: IV Bio.Natural-Bioactive Natural Products Research Meeting: Pharmacology Perspectives 17: 1728792. DOI: 10.3389/fphar.2026.1728792. LINK